泰诺福韦中间体 Intermediate of Tenofovir disoproxil fumarate:

3-[1-(dimethylamino)ethyl]phenol
CAS:63720-38-7
Structural formula:

Chloromethyl Chloroformate 氯甲酸氯甲酯
CAS: 22128-62-7
Structural formula:

Molecular Weight: 128.94
Appearance:Colorless and transparent liquid
Purity:98.0% min (By GC)
Moisture: 0.1%max.
Chloromethyl Isopropyl Carbonate 氯甲基异丙基碳酸酯
Synonym: Chloromethyl-2-Isopropyl Carbonate, CMIC
CAS: 35180-01-9
Structural formula:

Appearance:Colorless and transparent liquid
Purity:99.5% min (By GC)
Moisture: 0.1%max.
(R)-(+)-Propylene carbonate R-碳酸丙烯酯
Synonym: R-Propylene carbonate, RPC
CAS: 16606-55-6
Structural formula:

Appearance: Colorless and transparent liquid
Chemical purity: 99.0% min (By GC)
Enantionmeric excess: 99.0% (By GC)
(R)-9-(2-hydroxypropyl) adenine 9-(2-羟基丙基)腺嘌呤
Synonym: R-9-(2-hydroxypropyl) adenine, 9-HPA, (R)-9-[2-(hydroxy)propyl]adenine (HPA)
CAS: 14047-28-0
Structural formula: C8H11N5O

Molecular Weight: 193.21
Appearance: White powder
Purity: 98.0% min (By GC)
Enantionmeric excess: 98 % min (By GC)
Diethyl (tosyloxy) methylphosphonate 对甲苯磺酰氧甲基膦酸二乙酯
Synonym: Diethyl tosyloxy methylphosphonate, DESMP
CAS: 31618-90-3
Structural formula:

Molecular Weight: 322.31
Appearance: colorless to pale yellow oil
Purity:99.0% min (By HPLC)
Magnesium Tert Butoxide 叔丁醇镁
Synonym: Magnesium di-tert-butoxide
CAS: 32149-57-8
Molecular Formula:
(CH3)3COMgOC(CH3)3
Molecular Weight:
170.53
Structural formula:

Appearance: White to light grey powder
Assay: 95% min.
Moisture: 0.1%max.
(R)-9-[2-(phosphonomethoxy)propyl]adenine
(R)-9-(2-磷酸甲氧基丙基)腺嘌呤, 泰诺福韦
Synonym: (R)-PMPA, Tenofovir
CAS: 147127-20-6
Structural formula: 
Appearance: White or off-white crystalline powder
Assay: 98.0% min.
Metling point: 276-280°C
Tenofovir disoproxil (TD)
CAS: 201341-05-1
Tenofovir disoproxil fumarate (TDF,Viread)
CAS: 202138-50-9 |